After a decade of conflict, the humanitarian situation in Syria remains dire. Disruption of community networks, a collapsing economy, movement restrictions and the COVID-19 pandemic have exacerbated health and protection needs, especially for women and girls. Attacks on health facilities and workers still regularly occur. UNFPA is working to ensure continuity of services for sexual and reproductive health and gender-based violence, via a network of partner-administered facilities, and through provision of essential supplies. In response to COVID-19, UNFPA has also partnered with the World Food Programme to provide pregnant and lactating women with electronic vouchers to purchase essential hygiene items, simultaneously supporting both women’s autonomy and local markets.